Overactive Bladder

Overactive bladder (OAB) is a condition characterized by sudden, uncontrollable urges to urinate, often leading to involuntary urine leakage (urge incontinence). It significantly affects quality of life and daily activities.

Symptoms

Urgency

Sudden, strong need to urinate.

Frequency

Urinating more than eight times in 24 hours.

Nocturia

Waking up at night multiple times to urinate.

Urge Incontinence

Involuntary loss of urine after feeling a sudden urge to urinate.

Causes

Neurological Disorders

Conditions like Parkinson's disease, multiple sclerosis, and stroke.

Muscle Overactivity

Detrusor muscle in the bladder contracts inappropriately.

Medications

Diuretics and drugs affecting bladder function.

Bladder Irritants

Caffeine, alcohol, and spicy foods.

Risk Factors

Aging

Bladder muscles weaken with age.

Diabetes

Affects bladder nerve function.

Obesity

Increases pressure on the bladder.

Menopause

Hormonal changes affecting bladder function.

Investigations

Medical History and Symptom Diary

Detailed record of urinary habits and symptoms.

Urine Analysis

To rule out infections or blood in urine.

Bladder Diary: Record of fluid intake, urination times, and urine volumes.

Urodynamic Testing: Measures bladder pressure and urine flow.

Management

Bladder Infiltration

Injections of botulinum toxin (Botox) to relax the bladder muscles and reduce overactivity.

Medications

Anticholinergics: To relax bladder muscles.

Beta-3 Agonists: To relax the bladder and increase storage capacity.

Behavioral Therapies

Bladder Training: Scheduled urination to control urges.

Pelvic Floor Exercises: Strengthening pelvic muscles to improve control.

Lifestyle Modifications

Reducing caffeine and alcohol intake, managing fluid consumption.

Surgical Interventions:

Neuromodulation: Electrical stimulation of nerves controlling bladder function.

Cystectomy: Removal of the bladder in severe, refractory cases.

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